Acne Unit
At our clinics in Madrid: Calle Serrano 143 and La Moraleja
Recognised reference clinics in Spain
Home > Clinical Dermatology > Acne
What sets us apart
Comprehensive and personalised approach
The Grupo Pedro Jaén Acne Unit addresses this pathology in a holistic way, treating both active outbreaks and scars from the first consultation. We have the most advanced diagnostic technology to differentiate acne from other inflammatory skin diseases and design treatments adapted to each patient. In addition, we work closely with other specialties such as endocrinology, gynaecology and nutrition to identify underlying factors and optimise outcomes. Our approach combines medical therapies, laser technology and aesthetic solutions to improve the health and appearance of the skin.
What is acne, symptoms and treatment
A guide to understanding acne
Acne is a condition caused by inflammation of the pilosebaceous units, anatomical structures that include the hair follicle, the sebaceous gland—responsible for producing the lipids that form part of the hydrolipidic film protecting the skin—and the arrector pili muscle, which is responsible for phenomena such as goosebumps in response to certain stimuli.
Causes of acne
Acne develops as a result of a combination of factors, including genetic predisposition, hormonal changes, stress, the use of certain medications such as corticosteroids, the accumulation of dead skin cells, and the activity of the bacterium Cutibacterium acnes. These factors lead to obstruction and inflammation of the pilosebaceous unit, giving rise to comedones, the characteristic lesions of acne. These lesions are most commonly located in areas with a higher density of sebaceous glands, such as the face, back, chest, shoulders and, in some cases, the upper arms.
Symptoms and manifestations of acne
The most common acne lesions are open and closed comedones, commonly known as spots, pimples and blackheads.
Closed comedones, or inflammatory spots, may be raised to varying degrees, are usually reddish in colour and can be painful to the touch, particularly in certain areas of the face. In some cases, they may accumulate pus at their tip.
Open comedones, or blackheads, do not usually present with inflammation, although the follicular opening remains blocked. They are not painful, and their characteristic dark colour is caused by oxidation of keratin and other substances within the comedone when exposed to air.
Less commonly, acne may present with deeper inflammatory lesions in the form of pustules, cysts and nodules. In more severe cases, these lesions can be very painful and may even lead to abscess formation and systemic symptoms such as fever.
Diagnosis of acne
The diagnosis of acne is primarily clinical and is made during a dermatological consultation through examination of the skin. In some cases, acne specialists may consider additional laboratory or hormonal tests in order to tailor the diagnosis to each patient’s individual profile.
At the Grupo Pedro Jaén Acne Unit, we emphasise differential diagnosis in order to establish a personalised treatment plan aimed at resolving acne and preventing sequelae such as marks and irreversible scarring. For this reason, our dermatologists manage each case individually, taking into account the patient’s age, the characteristics of their lesions (predominantly inflammatory, presence of cysts, etc.) and their clinical and personal circumstances, such as pregnancy, breastfeeding or the presence of other conditions whose treatment may not be compatible with acne therapies.
A thorough assessment by our acne specialists also makes it possible to rule out associated conditions that may explain the skin lesions and, when necessary, refer the patient to the appropriate specialist to address the underlying pathology.
Types of acne
The most common types of acne include:
Neonatal acne and infantile acne
As mentioned above, acne is not exclusive to adolescence. Infants and young children may also be affected. Neonatal acne appears within the first weeks of life and may even be present in newborns. Infantile acne typically begins between four and six months of age and may persist until the child is two or three years old.
Both forms occur more frequently in boys than in girls and present with skin manifestations similar to those of adolescent acne, including comedones and inflammatory lesions, which are particularly common in neonatal patients.
Diagnosis is usually clinical, although depending on the context, additional tests may be required and referral to a paediatrician may be necessary, as some cases of infantile acne can be associated with mild forms of congenital adrenal hyperplasia or other hormonal alterations.
Adolescent acne
Adolescent acne is the most prevalent form of this dermatological condition and is often one of the main health concerns for patients in this age group, both because of its aesthetic impact and its emotional consequences.
It is estimated that around 80% of adolescents experience acne to some degree. While acne was once considered a transient condition that did not require treatment, current dermatological practice strongly supports early diagnosis and treatment to prevent immediate skin damage and long-term aesthetic sequelae. Scientific evidence shows that the longer acne persists, the higher the risk of residual marks, pigmentation changes and scarring.
Effective acne treatment is also important for emotional wellbeing, as acne has been shown to significantly affect self-esteem and psychological balance in young people.
Typical lesions of adolescent acne are closely linked to hormonal changes during puberty. Acne usually appears around the age of 11, persists chronically or intermittently until approximately 15 years of age, and gradually improves between the ages of 18 and 20.
Comedones are most commonly distributed in areas of the face with a higher concentration of sebaceous glands, known as the T-zone (forehead, nose and chin), as well as the cheeks. In more severe cases, acne lesions may also affect the chest, back and upper arms, particularly in male patients.
Boys often develop more severe forms of adolescent acne due to the influence of testosterone and the fact that male skin tends to be thicker and contains a higher density of sebaceous glands, which favours follicular obstruction.
Girls, by contrast, tend to experience less aggressive but more persistent acne. In many cases, acne worsens during the second half of the menstrual cycle, as sebum production increases in the days leading up to menstruation.
Adult acne
Adult acne is an increasingly common reason for dermatological consultation. It affects patients over the age of 25 and is classified as persistent adult acne—when it has been present since adolescence—or late-onset adult acne, when it develops after the age of 25.
Adult acne is significantly more common in women than in men (approximately 30% compared to less than 10%) and often presents in a more severe inflammatory form. For this reason, it is frequently referred to as acne in adult women.
Although the types of lesions are similar to those seen in adolescent acne, their distribution differs. Adult acne typically follows a U-shaped pattern, affecting the jawline, perioral area and neck, rather than the T-zone characteristic of younger patients.
Diagnosis and treatment are often influenced by hormonal factors and by the greater inflammatory component of lesions at this age, which increases the risk of scarring.
Other types of acne
Some less common forms of acne require specific treatment approaches, depending on the dermatologist’s diagnosis:
Summer acne (Mallorca acne)
This form of acne is triggered by ultraviolet radiation. It is more inflammatory and aggressive than common acne and usually affects the upper torso and arms of individuals who have current or previous acne and are exposed to the sun without adequate photoprotection.
Although sun exposure may temporarily dry the skin and reduce inflammation, this improvement is short-lived. Sun exposure thickens the outermost layer of the skin, promoting follicular obstruction and often causing a rebound worsening of acne at the end of summer.
There is also a misconception that people with acne should avoid sunscreen. In reality, modern oil-free sunscreens are available and may even include active ingredients that help treat acne.
Frictional acne
Also known as mechanical acne, this form results from prolonged friction and contact between sweat and areas of the skin subjected to pressure from clothing, such as straps, belts or sportswear. Sweat irritates the skin, increases sebum production and promotes follicular obstruction. Frictional acne is relatively common in athletes and may cause itching. Scratching can worsen lesions, spread bacteria and further damage the skin.
Acne excoriée
This form of acne results from repeated and compulsive picking or scratching of lesions, leading to prominent marks and scarring. Rather than eliminating comedones, these behaviours promote bacterial spread and worsen skin damage. It most commonly affects the face, as it is easily accessible.
Drug-induced acne
This type of acne is caused by certain medications, such as corticosteroids, barbiturates or oral contraceptives. Treatment depends on identifying and managing the triggering medication.
Inverse acne
Inverse acne occurs when sweat glands in areas such as the armpits, groin and under the breasts become obstructed, leading to inflammation and the formation of painful nodules. Treatment is important, as lesions tend to recur and may leave hyperpigmentation or scarring.
“In most cases, the best results are achieved by combining several therapeutic options and initiating treatment early.”
Acne treatments
There are several treatment options for acne, which the specialists at the Grupo Pedro Jaén Acne Unit apply on an individual basis according to each patient’s specific situation. In most cases, the best results are achieved by combining different therapeutic approaches and initiating treatment early, allowing the condition to improve as quickly as possible while preventing relapses, progression or long-term sequelae.
When deciding on the most appropriate treatment, the dermatologist will also take into account factors such as the patient’s age, pregnancy status, the presence of marks or scars, the type and condition of comedones (open or closed), the degree of inflammation, the areas affected, the possibility of using treatments with an additional anti-ageing effect, and whether laser sessions should be added to topical or oral therapies.
Topical treatments
Topical acne treatments may be formulated as gels, masks, creams or lotions. They contain different active ingredients —such as alpha hydroxy acids, azelaic acid, beta hydroxy acids or benzoyl peroxide— at varying concentrations:
- Sebum-regulating agents. Which help control excessive oil production
- Keratolytic agents. Which prevent the accumulation of keratin and obstruction of the pilosebaceous unit, refining the skin surface.
- Comedolytic agents. Which help eliminate pimples and blackheads.
Our dermatologists select the most appropriate option for each patient, bearing in mind that higher concentrations of active ingredients may be more effective but also carry a greater risk of skin irritation.
For this reason, lower concentrations are usually recommended for more sensitive skin, while higher concentrations are introduced progressively as the skin tolerates treatment better. Regular follow-up by the acne specialist is essential to monitor progress and adjust doses according to clinical response and skin tolerance.
Oral treatments
Several oral therapeutic options are available for the treatment of acne and must be prescribed by a dermatologist on a case-by-case basis. These treatments aim to control sebum production, reduce inflammation, eradicate Cutibacterium acnes—a bacterium closely linked to acne that feeds on sebum and cellular debris—balance the hormonal profile when excessive oil production is hormonally driven, and further reduce inflammatory activity.
The goal of these therapies, which are increasingly safe and effective when used at minimal doses, is to control acne while preventing marks, scarring or pigmentation disorders associated with this skin condition.
As these medications require a prescription, it is essential that each patient consults with a dermatologist to design an individualised treatment plan. This allows the therapy to target acne triggers, control flare-ups and prevent or treat sequelae such as marks and scars.
Laser treatments
Laser therapy has gained an increasingly important role in acne management due to the wide range of technologies available. Current scientific evidence supports the use of laser treatments for acne, usually in combination with other therapies and, depending on the case, using different types of laser.
According to the type of acne, its manifestations and potential sequelae, the following options are available:
Pulsed dye laser
Used to reduce inflammation associated with comedones and acne-related cysts, accelerating lesion resolution.
Vascular laser
Helps reduce inflammation, attenuate redness and improve the overall appearance of the skin.
Pigment laser
Used to lighten post-acne hyperpigmented marks and scars, a common concern particularly in patients with darker skin tones.
Ablative and non-ablative fractional laser
These devices may be used alone or in combination to treat skin atrophy and acne scars.
The dermatologists at our Acne Unit are highly experienced in the use of different laser technologies for the treatment of acne. They are also supported by the technology and specialists of the Grupo Pedro Jaén Laser Unit—the most comprehensive laser platform in Europe’s private sector—ensuring optimal treatment selection and maximum effectiveness.
Regardless of the therapeutic protocol recommended, it is essential that patients follow medical instructions carefully in order to resolve lesions, improve skin appearance, prevent recurrences and avoid the development of scars, marks or pigmentation changes.
Biophotonic therapy for acne
Biophotonic therapy involves the application of a device with three panels emitting high-intensity LED blue light at a short distance from the patient’s skin, after a photoconverter gel has been applied.
The light emitted by the biophotonic device eliminates bacteria and exerts an anti-inflammatory effect on acne lesions. It also activates microcirculation in the treated area, normalises cellular activity and reduces redness. In addition, it stimulates the skin’s natural collagen production, contributing to the reduction of acne scars and improving overall skin quality.
One of the main advantages of biophotonic therapy is that it is suitable for all forms of acne, including more severe cases. The treatment consists of several sessions lasting just nine minutes each, delivered over a six-week period. It is painless and significantly improves skin quality, which is why it is also used as a skin rejuvenation therapy.
After each session, a moisturising cream—preferably with sun protection factor—is applied, and patients can immediately resume their normal social and professional activities. Make-up may be used, provided oil-free formulations are chosen. Adequate hydration is also recommended.
Acne lesions improve in approximately 90% of patients within 12 weeks of starting treatment. Results continue to improve in the weeks following completion of therapy.
More information
Below you will find the frequently asked questions, the authorship, and the references for the information provided on this page
Frequently asked questions about acne
Do certain foods cause acne?
Some studies have linked diets high in refined sugars, ultra-processed foods and dairy products to acne. However, the association between acne and specific foods such as chocolate or fried foods is largely based on myths. Unless there are food allergies or intolerances, consuming a specific food does not directly worsen acne or skin condition.
Does stress cause acne?
Stress and emotional tension are not direct causes of acne. However, as with other dermatological conditions such as rosacea, psoriasis or atopic dermatitis, stress can exacerbate existing acne, as they share certain biochemical mechanisms.
Does sun exposure cure acne?
It is often said that acne improves in summer due to sun exposure. While sunlight has a temporary anti-inflammatory and drying effect, hormonal factors and increased sebum production remain unchanged, meaning acne is not cured by sun exposure. Moreover, ultraviolet radiation can worsen hyperpigmentation and contribute to persistent marks and scars.
Sun exposure also thickens the outer layer of the skin, promoting follicular obstruction and frequently causing a rebound worsening of acne at the end of summer.
Why shouldn’t you squeeze pimples?
Picking or squeezing acne lesions should be avoided. This behaviour increases the risk of infection by spreading bacteria and traumatising the skin, which in turn raises the likelihood of marks and scars that may require specific treatment.
The best approach is patience and the use of dermatologist-prescribed products designed to reduce inflammation and unclog the pilosebaceous pore.
Are oral acne medications safe?
Yes, when prescribed and monitored by a dermatologist. Oral acne treatments are not available over the counter and must be supervised to ensure safety and minimise side effects.
Facial cleansing and acne: is more always better?
Excessive cleansing and exfoliation can irritate the skin and cause rebound acne. Dermatologists recommend gentle cleansing with products designed for acne-prone skin, oil-free cosmetics and sun protection using oil-free sunscreens that may also contain acne-treating ingredients.
How can I care for acne-prone skin?
Cleanse the skin with products formulated for acne-prone skin to remove excess sebum and unclog pores.
Use oil-free, lightweight and non-comedogenic cosmetics and make-up. Do not share them and clean brushes and sponges regularly.
Avoid self-diagnosis and self-medication. A dermatologist is best placed to treat acne effectively.
Attend specialised aesthetic centres periodically for professional acne-specific facial treatments.
Authorship and references
The content of this page has been prepared by the Communication Department and the Medical Team of Grupo Pedro Jaén, in line with our editorial commitment to ensuring the accuracy and up-to-date nature of the information provided.
Acne references:
1. Gabriella Fabbrocini, corresponding author Sara Cacciapuoti, and Giuseppe Monfrecola. A Qualitative Investigation of the Impact of Acne on Health-Related Quality of Life (HRQL): Development of a Conceptual Model. Dermatol Ther (Heidelb). 2018 Mar; 8(1): 85–99. Published online 2018 Feb 12. doi: 10.1007/s13555-018-0224-7. PMCID: PMC5825329. PMID: 29435857.
2. A.U. Tan, MD,⁎ B.J. Schlosser, MD, PhD, and A.S. Paller, MD. A review of diagnosis and treatment of acne in adult female patients. Int J Womens Dermatol. 2018 Jun; 4(2): 56–71. Published online 2017 Dec 23. doi: 10.1016/j.ijwd.2017.10.006. PMCID: PMC5986265. PMID: 29872679.
3. Alexander KC Leung,corresponding author Benjamin Barankin, Joseph M Lam, Kin Fon Leong and Kam Lun Hon. Dermatology: how to manage acne vulgaris. Drugs Context. 2021; 10: 2021-8-6. Published online 2021 Oct 11. doi: 10.7573/dic.2021-8-6. PMCID: PMC8510514. PMID: 34691199.
4. Darren D Lynn, Tamara Umari, Cory A Dunnick and Robert P Dellavalle. The epidemiology of acne vulgaris in late adolescence. Adolesc Health Med Ther. 2016; 7: 13–25. Published online 2016 Jan 19. doi: 10.2147/AHMT.S55832. PMCID: PMC4769025. PMID: 26955297.
5. Jianting Yang, Haoran Yang, Aie Xu, and Li He. A Review of Advancement on Influencing Factors of Acne: An Emphasis on Environment Characteristics. Front Public Health. 2020; 8: 450. Published online 2020 Sep 17. doi: 10.3389/fpubh.2020.00450 PMCID: PMC7527424. PMID: 33042936.
6. Zaenglein AL, Pathy AL, Schlosser BJ, Alikhan A, Baldwin HE, Berson DS, Bowe WP, Graber EM, Harper JC, Kang S, Keri JE, Leyden JJ, Reynolds RV, Silverberg NB, Stein Gold LF, Tollefson MM, Weiss JS, Dolan NC, Sagan AA, Stern M, Boyer KM, Bhushan R. Guidelines of care for the management of acne vulgaris. J Am Acad Dermatol. 2016 May;74(5):945-73.e33. doi: 10.1016/j.jaad.2015.12.037. Epub 2016 Feb 17. Erratum in: J Am Acad Dermatol. 2020 Jun;82(6):1576. PMID: 26897386.
7. John S. Strauss,Daniel P. Krowchuk,James J. Leyden,Anne W. Lucky,Alan R. Shalita,Elaine C. Siegfried,Diane M. Thiboutot,Abby S. Van Voorhees,Karl A. Beutner,Carol K. Sieck,Reva Bhushan. Guidelines of care for acne vulgaris management. Journal of the American Academy of Dermatology Volume 56, Issue 4, April 2007, Pages 651-663. DOI: 10.1016/j.jaad.2006.08.048.
8. B Dréno. What is new in the pathophysiology of acne, an overview. J Eur Acad Dermatol Venereol. 2017 Sep;31 Suppl 5:8-12. doi: 10.1111/jdv.14374. PMID: 28805938.
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Clinics in Madrid
Grupo Pedro Jaén is a medical group founded more than three decades ago with the aim of providing medical, surgical and aesthetic solutions related to skin health and appearance. Led by Dr Pedro Jaén, the group has a highly specialised medical team that covers every area of care with top-level specialists, carries out extensive training activities, is a leader in medical research, and operates several clinics in Madrid, from which it offers the highest standards of care and clinical excellence to all patients.
Calle Serrano 143
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Calle Serrano 143, El Viso neighbourhood, Chamartín district, 28006 Madrid, Spain
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Calle de la Estafeta 8, ground floor, La Moraleja, 28109 Alcobendas, Madrid
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