Polynucleotide Treatment
At our clinics in Madrid: Calle Serrano 143 and La Moraleja
Specialists in
Polynucleotide Treatment
Polynucleotides are biological molecules used in aesthetic dermatology and aesthetic medicine to stimulate the skin’s natural dermal repair mechanisms. Their aim is to improve skin quality from within, supporting elasticity, texture and radiance without increasing volume or altering facial expression. Suitable for women and men seeking progressive, natural-looking rejuvenation, polynucleotide treatment is performed after an individual dermatological assessment, allowing the indication, treatment protocol and follow-up to be defined according to the condition of the skin and the therapeutic goals.
Recognised reference clinics in Spain
Home > Regenerative Medicine > Polynucleotides
What sets us apart
Dermatological judgement and a rigorous medical approach
At Grupo Pedro Jaén, this procedure is performed under specialised medical supervision. Its incorporation into aesthetic practice is supported by its previous use in other medical areas related to tissue regeneration, providing a solid scientific basis. The indication is established after a personalised clinical assessment, prioritising safety, biocompatibility and natural-looking results. The treatment is integrated into a coherent plan aimed at progressively improving skin quality while respecting facial anatomy.
Personalised medical indication
Skin biostimulation without increasing volume
Global dermatological strategy
Personalised medical indication
Polynucleotide treatment is not indicated in a standardised way. Before performing the procedure, the condition of the skin, the degree of photoageing and the specific therapeutic goals are assessed, such as improving texture, elasticity or dermal quality. The decision is based on dermatological diagnosis and objective clinical criteria, avoiding generic protocols. This assessment makes it possible to determine whether the treatment is appropriate or whether it should be integrated into a broader skin rejuvenation plan.
Individualised treatment plan
A protocol is defined according to the patient’s skin needs, medical history and expectations, adjusting the number of sessions and reviews according to clinical progress.
Safety and specialised medical setting
The procedure is performed at our reference dermatology clinics in Madrid, prioritising biocompatibility, medical control and natural-looking results.
Skin biostimulation without increasing volume
Polynucleotides act by stimulating the skin’s natural dermal repair mechanisms. They are not designed to add volume or modify facial proportions, but to improve the quality of skin tissue from within. This approach makes it possible to rejuvenate the skin while maintaining the identity and natural expression of the face, without creating artificial changes.
Respect for facial anatomy
The treatment optimises texture, firmness and elasticity without altering facial structure. Its aim is to reinforce dermal quality and promote more resilient, balanced skin.
Progressive and physiological results
Improvement appears gradually, in line with the biological timing of tissue regeneration. This supports discreet, coherent and sustainable results over time.
Global dermatological strategy
When indicated, polynucleotide treatment can be integrated into a broader dermatological plan aimed at improving skin quality. It is not conceived as an isolated procedure, but as a tool within a structured strategy, always under medical planning and with therapeutic coherence.
Structured clinical follow-up
A sequence of sessions and reviews is planned according to each case, making it possible to assess progress, clinical response and stability of results.
Global view of skin quality
The aim is not a one-off improvement, but the sustainable optimisation of the skin within a dermatological strategy based on scientific evidence.
Where we see patients?
Clinics in Madrid
Grupo Pedro Jaén is a medical group founded more than three decades ago with the aim of providing medical, surgical and aesthetic solutions related to skin health and appearance. Led by Dr Pedro Jaén, the group has a highly specialised medical team that covers every area of care with top-level specialists, carries out extensive training activities, is a leader in medical research, and operates several clinics in Madrid, from which it offers the highest standards of care and clinical excellence to all patients.
Calle Serrano 143
This centre is the main headquarters of Grupo Pedro Jaén. It provides diagnostic and treatment services in skin cancer, clinical and aesthetic dermatology, laser treatments and other related specialties.
Mon - Fri 09:00 - 21:00 / Sat: 09:00 - 14:00
Calle Serrano 143, El Viso neighbourhood, Chamartín district, 28006 Madrid, Spain
La Moraleja
Located in Plaza de La Moraleja, this exclusive centre allows Grupo Pedro Jaén to bring its medical and aesthetic services closer to patients across the entire northern area of Madrid.
Mon - Thu: 09:30 - 20:00 / Fri: 09:30 - 18:00
Calle de la Estafeta 8, ground floor, La Moraleja, 28109 Alcobendas, Madrid
General information and FAQs
A guide to complementary body treatments
Complementary body treatments are designed to improve body skin quality and optimise aspects related to firmness, drainage and body reshaping. Their purpose is not only to achieve an immediate effect, but to maintain a progressive evolution aligned with the condition of the tissues.
In many cases, these treatments complement a healthy lifestyle based on physical exercise, a balanced diet and adequate rest. When applied with professional judgement and consistency, they help improve skin texture, skin evenness and the sensation of bodily lightness.
At Grupo Pedro Jaén, protocols can be integrated into a global dermatological and aesthetic care strategy, maintaining coherence between skin health and aesthetic goals.
Frequently asked questions
Can I have a body treatment during pregnancy?
Some manual treatments can be carried out during pregnancy, especially those aimed at drainage and relieving fluid retention. Other procedures involving devices should be postponed. A prior assessment is essential in order to adapt the protocol to each situation.
Can different body treatments be combined?
Yes. Many body treatments can be combined with one another to enhance results, always after an individual assessment. The choice depends on the goal: firmness, drainage, improvement of cellulite or body reshaping.
Do body treatments with devices hurt?
They should not be painful. Some may generate a sensation of warmth or controlled pressure, always within safe parameters. The professional supervises the session to guarantee comfort.
How many sessions are needed to notice results?
This depends on the goal and the type of treatment. Some produce visible improvement from the first session; others require several sessions to achieve progressive results. Consistency and healthy habits influence how long the effects last.
Authorship and references
The content of this page has been prepared by the Communication Department and the Medical Team of Grupo Pedro Jaén, in line with our editorial commitment to ensuring the accuracy and up-to-date nature of the information provided.
Related units and pages
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Minimally invasive treatments to improve facial appearance with harmonious and natural-looking results.
Body aesthetics
A personalised approach combining different treatment strategies to address the main body-related concerns.
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Surgical and aesthetic treatments fully adapted to male facial and body anatomy.
Scars
Fully personalised treatments tailored to the type and specific characteristics of each scar.
Plastic surgery
Treatment of facial and body aesthetic and functional concerns that require a surgical solution.
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Cosmetic and aesthetic treatments that address beauty from a clinical perspective to achieve optimal results.
Information and news
Press room
In the Grupo Pedro Jaén Press Room you can find information, advice and news related to dermatology, aesthetic medicine, trichology and general health. The group’s journals are also shared through an online platform, along with updates on the activity and media appearances of our clinics and healthcare professionals.
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Blog
News about Grupo Pedro Jaén. Information and advice on dermatology, aesthetic medicine, trichology, and general health
Media
Information about media appearances by our clinics and medical specialists.
Journal
Archive of all Grupo Pedro Jaén journals, available through an external online platform.