In this article, we explain the main indications, benefits and contraindications of glycolic acid for the skin.

Glycolic acid is a common ingredient in skincare products because of its effects on skin texture and renewal.

It belongs to the group of alpha hydroxy acids (AHAs). These compounds occur naturally in substances such as fruit, milk and sugar cane. Their main action is keratolytic: they act on the epidermis and promote renewal of the stratum corneum, helping to improve the appearance and texture of the skin.

Glycolic acid is derived from sugar cane. It has a relatively low molecular weight, which facilitates penetration into the skin. It also has moisturising properties, promotes keratinocyte turnover and may stimulate collagen production.

Indications, contraindications and benefits of glycolic acid for the skin

Glycolic acid is primarily used as an exfoliating agent to help remove dead cells from the skin surface. It is also a common ingredient in medical chemical peels performed in aesthetic dermatology. Depending on the concentration and indication, these treatments can help even out skin tone, reduce the appearance of pigmentation, improve the appearance of enlarged pores and smooth skin texture. Different concentrations of glycolic acid are used depending on the intended effect.

Indications for glycolic acid in skincare

Glycolic acid is also frequently used to improve the appearance of acne-prone skin, as its exfoliating effect can help remove superficial dead skin cells and improve skin texture. It may also facilitate penetration of topical products prescribed by a dermatologist for the treatment of acne.

Glycolic acid can be used on many skin types, although it may not be appropriate for very sensitive skin, as it can cause irritation and peeling. It should always be used at the concentration and frequency recommended by the dermatologist. Combining it with other active ingredients without appropriate guidance should be avoided, as this may increase the risk of irritation or other adverse reactions.

Mild burning, stinging or itching may occasionally occur after application, particularly when the product is first introduced. If symptoms are persistent, intense or worsen, the product should be discontinued and medical advice sought.

It is advisable to consult a dermatologist specialising in aesthetic dermatology about the most appropriate products for an individual skin type and how they should be introduced. This allows treatment to be adapted to the patient’s needs, helps minimise adverse reactions and makes it possible to modify the regimen when the condition of the skin changes.

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Authorship and references

The content of this article has been prepared by the Grupo Pedro Jaén Communications Department and Medical Team in accordance with our editorial commitment, which ensures the accuracy and regular updating of the information provided.

References on the benefits and indications of glycolic acid for the skin:

1. Sharad J. Glycolic acid peel therapy – a current review. Clin Cosmet Investig Dermatol. 2013 Nov 11;6:281-8. doi: 10.2147/CCID.S34029. PMID: 24399880; PMCID: PMC3875240.

2. Yu RJ, Van Scott EJ. Alpha-hydroxyacids and carboxylic acids. Journal of Cosmetic Dermatology. 2004;3:76-87. doi: 10.1111/j.1473-2130.2004.00059.x. https://doi.org/10.1111/j.1473-2130.2004.00059.x

3. Tang SC, Yang JH. Dual Effects of Alpha-Hydroxy Acids on the Skin. Molecules. 2018 Apr 10;23(4):863. doi: 10.3390/molecules23040863. PMID: 29642579; PMCID: PMC6017965.

4. Sharad J. Combination of microneedling and glycolic acid peels for the treatment of acne scars in dark skin. J Cosmet Dermatol. 2011 Dec;10(4):317-23. doi: 10.1111/j.1473-2165.2011.00583.x. PMID: 22151943.

5. Houshmand EB. Effect of glycolic acid, phytic acid, soothing complex containing Emulsion on Hyperpigmentation and skin luminosity: A clinical evaluation. J Cosmet Dermatol. 2021 Mar;20(3):776-780. doi: 10.1111/jocd.13950. Epub 2021 Feb 2. PMID: 33458927.