Alopecia androgénica

Treatment at our clinics in Madrid on Calle Cinca and La Moraleja

Dermatologists specialising in

Treatment of male and female androgenetic alopecia

Therapies for androgenetic alopecia have undergone a true revolution over the last decade, a process in which the specialists of the Grupo Pedro Jaén Hair Disorders and Hair Transplant Unit have actively participated, leading several of the most relevant scientific studies in this field. Treatment for androgenetic alopecia may be medical (topical, oral or injectable therapies) or surgical (hair transplantation), depending on the characteristics and stage of the condition.

Dermatologists specialised in the treatment of androgenetic alopecia in Madrid (Spain). Clinics on Calle Cinca and La Moraleja.

Recognised reference clinics in Spain

Home > Hair Disorders Unit > Androgenetic alopecia

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We address androgenetic alopecia, a condition that affects both men and women, through a comprehensive and personalised medical approach. By combining advanced diagnostic tools with tailored treatment strategies, we aim to slow disease progression and stimulate hair regrowth. Our team of dermatologists specialised in hair disorders, with extensive experience in both clinical practice and research, focus on achieving long-term, sustainable results based on scientific evidence.

Alopecia androgénica

More information about the condition and our specialists

What it is, types, causes and treatment

A guide to understanding androgenetic alopecia

Androgenetic alopecia, also known as androgenetic hair loss, is the most common form of alopecia among the more than 100 types currently described. It is estimated to affect approximately 40% of men between the ages of 18 and 39, and up to 95% of men over the age of 70. In fact, androgenetic alopecia is so frequent in men that it is often considered a near-physiological process.

Although androgenetic alopecia is primarily associated with men due to the role of androgens (male hormones) in its development, it can also affect women throughout their lives, albeit to a lesser extent. It is estimated that female androgenetic alopecia affects around 35% of women of reproductive age and up to 50% of women after menopause.

Hair loss of this type can be particularly distressing for female patients, often leading to a significant impact on emotional wellbeing and self-esteem.

Information about male and female androgenetic alopecia

Male androgenetic alopecia

The characteristic clinical feature of male androgenetic alopecia is a progressive reduction in hair density, resulting in visible thinning of the scalp. The areas most commonly affected are the frontal region (receding hairline) and the vertex (crown). However, some patients present with diffuse thinning across the entire upper scalp.

In the early stages, many patients only notice reduced density when the hair is wet or under strong lighting. Male androgenetic alopecia is classified into seven stages according to the Norwood scale, with grade I being the mildest and grade VII the most advanced. Not all patients progress to advanced stages, although without treatment, hair loss typically follows a slow but progressive course, particularly during younger adulthood.

Female androgenetic alopecia

The main clinical difference between male and female androgenetic alopecia is the absence, in most women, of the classic receding hairline or vertex balding pattern. Instead, female androgenetic alopecia usually presents as diffuse thinning, with increased scalp visibility, particularly under bright light.

The most commonly affected areas are the central frontal and parietal regions, with progressive widening of the central parting while preserving the frontal hairline. Over time, diffuse thinning may extend across the entire upper scalp.

Female androgenetic alopecia is classified into three stages according to the Ludwig or Olsen scales, from grade I (mild) to grade III (advanced). Using the Ebling scale, five stages are described. As in men, not all women progress to advanced stages, but without medical treatment, hair loss generally follows a slow and sustained course.

In most cases, not all patients with androgenetic alopecia will progress to the most advanced stages of hair loss. However, if medical treatment is not prescribed, the course of female androgenetic alopecia—similar to that observed in male androgenetic alopecia—is typically slow but progressive.

Causes and diagnosis of androgenetic alopecia

The causes of both male and female androgenetic alopecia are primarily genetic and hormonal. Early diagnosis is possible, even before hair loss becomes clinically evident.

Causes of male and female androgenetic alopecia

Male androgenetic alopecia is mainly driven by genetic predisposition and hormonal factors. Although many affected men have a family history of the condition, the absence of such a history does not exclude the possibility of developing androgenetic alopecia.

Hair loss occurs because follicles in the frontal, vertex and upper scalp regions are more sensitive to androgens.

These hormones trigger a process known as follicular miniaturisation, in which hair follicles progressively decrease in diameter until they eventually stop producing visible hair if no treatment is initiated.. Male androgenetic alopecia usually begins between the ages of 20 and 25, although earlier onset is possible. It is generally not associated with underlying systemic disease.

In female androgenetic alopecia, although genetic and hormonal factors also play a central role, additional mechanisms may be involved that are not exclusively related to androgens.

This condition may begin as early as childhood, coinciding with adrenarche (the onset of adrenal hormone production), may develop before menopause, or may become more pronounced after menopause due to the physiological decline in oestrogen levels. When hair loss appears before menopause, it is referred to as early-onset female androgenetic alopecia; when it develops after menopause, it is classified as late-onset.

Family history is common but not universal. Unlike male androgenetic alopecia, the female form is frequently associated with concomitant conditions such as iron or vitamin deficiencies, eating disorders, restrictive diets, and hormonal disorders including polycystic ovary syndrome, HAIR-AN syndrome, congenital adrenal hyperplasia, or adrenal or ovarian tumours. For this reason, a thorough diagnostic evaluation is essential before initiating treatment.

Diagnosis of androgenetic alopecia

The diagnosis of androgenetic alopecia is primarily clinical and is performed by dermatologists specialised in hair disorders during consultation. Thanks to the advanced technology available in the Hair Disorders and Hair Transplant Unit of Grupo Pedro Jaén, diagnosis can be made at early stages, even when hair loss is not yet clearly visible.

Digital trichoscopy and video trichoscopy systems are used to obtain magnified images of the scalp, hair shafts and follicles. These tools allow accurate diagnosis, assessment of disease severity, treatment planning and medium- to long-term monitoring of disease progression.

In men, routine laboratory testing is not usually required, as male androgenetic alopecia is rarely associated with systemic disease. In women, however, comprehensive blood tests are often necessary to assess for hormonal or metabolic abnormalities that may contribute to hair loss.

“Although androgenetic alopecia is primarily associated with men, it can also affect women, albeit to a lesser extent”

Treatment of male and female androgenetic alopecia

The treatment of androgenetic alopecia may be medical (topical, oral or injected medication) or surgical (hair transplantation). In both cases, therapies for androgenetic alopecia have undergone a true revolution over the past decade, a process in which the specialists of the Hair Disorders and Hair Transplant Unit of Grupo Pedro Jaén have played an active role, leading several of the most relevant scientific studies in this field.

At present, there is no curative treatment for androgenetic alopecia. Available therapies must therefore be maintained over time in order to achieve sustained results. Although lifelong treatment is not usually necessary, it is well established that longer treatment duration is associated with better overall outcomes.

The main objectives of treatment are, first, to slow the progression of hair loss, and second, to increase hair density by thickening existing hair fibres that have undergone follicular miniaturisation.

The most common strategy adopted by the specialists at Grupo Pedro Jaén consists of implementing a more intensive treatment during the first two years following diagnosis, followed by a maintenance protocol thereafter, always adapted to the individual course of the condition.

This approach is based on the fact that the effects of treatment generally become noticeable after approximately six months, reaching their maximum efficacy between one and one and a half years. From that point onwards, a maintenance regimen can be considered, making long-term treatment more manageable for the patient.

The accumulated experience of the dermatologists specialised in hair disorders and hair transplantation at Grupo Pedro Jaén shows that the most effective approach is to combine different therapeutic strategies and adjust them over time according to the patient’s response and the evolution of their alopecia.

By doing so, we achieve a significant reduction in hair loss and a clear improvement in hair density, with effectiveness rates approaching 90% in a large proportion of treated cases. In fact, many patients who initially attend consultation seeking hair transplantation ultimately do not require surgery due to the favourable response obtained with medical treatment alone.

Currently, our Hair Disorders and Hair Transplant Unit, recognised as one of the most relevant at an international scientific level, offers all available therapeutic options for the treatment of androgenetic alopecia, including oral, topical and injected medications with proven efficacy and safety supported by robust scientific evidence.

Complementary medical therapies

Additional treatments may be useful in selected cases of androgenetic alopecia, including microneedling, mesotherapy combining different active compounds, low-level laser therapy, or prostaglandin analogues. Although regenerative therapies based on stem cells are under investigation, further research is still required before their routine clinical application.

In addition, the specialists at Grupo Pedro Jaén may consider prescribing complementary medical treatments based on abnormalities detected in laboratory tests or diagnostic studies, or in the presence of associated conditions that may coexist with androgenetic alopecia, such as iron deficiency anaemia or seborrhoeic dermatitis.

Hair transplantation for androgenetic alopecia

Hair transplantation is one of the therapeutic options for androgenetic alopecia. The Hair Disorders and Hair Transplant Unit of Grupo Pedro Jaén specialises in performing this procedure using follicular micrografting techniques, a minimally invasive surgical approach that can be used as a complement to medical treatment to significantly improve hair density in areas of established hair loss.

This procedure provides completely natural-looking results. Hair transplantation is mainly performed using the FUE technique (which can be done with or without shaving, depending on the case) or the FUSS technique. In all cases, the procedure is carried out in an operating theatre, does not require hospital admission, and recovery is usually complete within 7 to 8 days. New hair growth typically becomes visible after approximately six months, with the final result achieved between 12 and 15 months after surgery.

Clinic specialised in the treatment of male and female androgenetic alopecia in Madrid.

More information

Below you will find the authorship and references for the information provided on this page:

Authorship and references

The content of this page has been prepared by the Communication Department and the Medical Team of Grupo Pedro Jaén, in line with our editorial commitment to ensuring the accuracy and up-to-date nature of the information provided.

References on androgenetic alopecia:

1. New Treatments for Hair Loss. Vañó-Galván S, Camacho F. Actas Dermosifiliogr. 2017 Apr;108(3):221-228. doi: 10.1016/j.ad.2016.11.010.

2. Superiority of dutasteride over finasteride in hair regrowth and reversal of miniaturization in men with androgenetic alopecia: A randomized controlled open-label, evaluator-blinded study. Shanshanwal SJ, Dhurat RS. Indian J Dermatol Venereol Leprol. 2017 Jan-Feb;83(1):47-54.

3. Effectiveness and safety of oral dutasteride for male androgenetic alopecia in real clinical practice: A descriptive monocentric study. Vañó-Galván S, Saceda-Corralo D, Moreno-Arrones OM, Rodrigues-Barata R, Morales C, Gil-Redondo R, Bernárdez-Guerra C, Hermosa-Gelbard Á, Jaén-Olasolo P. Dermatol Ther. 2020 Jan;33(1):e13182. doi: 10.1111/dth.13182.

4. Long-term safety and efficacy of dutasteride in the treatment of male patients with androgenetic alopecia. Tsunemi Y, Irisawa R, Yoshiie H, Brotherton B, Ito H, Tsuboi R, Kawashima M, Manyak M; ARI114264 Study Group. J Dermatol. 2016 Sep;43(9):1051-8.

5. A randomized, active- and placebo-controlled study of the efficacy and safety of different doses of dutasteride versus placebo and finasteride in the treatment of male subjects with androgenetic alopecia. Gubelin Harcha W, Barboza Martínez J, Tsai TF, Katsuoka K, Kawashima M, Tsuboi R, Barnes A, Ferron-Brady G, Chetty D. J Am Acad Dermatol. 2014 Mar;70(3):489-498.e3.

6. Mesotherapy with dutasteride in the treatment of androgenetic alopecia. Saceda-Corralo D, Rodrigues-Barata AR, Vano-Galvan S, Jaen-Olasolo P. Int J Trichol 2017;9:143-5.

7. Effectiveness and safety of low-dose oral minoxidil in male androgenetic alopecia. Jimenez- Cauhe J, Saceda-Corralo D, Rodrigues-Barata R, Hermosa-Gelbard A, Moreno-Arrones OM Fernandez-Nieto D, Vaño-Galvan S. J Am Acad Dermatol. 2019 Aug;81(2):648-649.

8. Safety of low-dose oral minoxidil treatment for hair loss. A systematic review and pooled-analysis of individual patient data. Jimenez-Cauhe J, Saceda-Corralo D, Rodrigues-Barata R, Moreno-Arrones OM, Ortega-Quijano D, Fernandez-Nieto D, Jaen-Olasolo P, Vaño-Galvan S. Dermatol Ther. 2020 Aug 5. doi: 10.1111/dth.14106.

9. Safety and Tolerability of the Dual 5-Alpha Reductase Inhibitor Dutasteride in the Treatment of Androgenetic Alopecia. Choi GS, Kim JH, Oh SY, Park JM, Hong JS, Lee YS, Lee WS. Ann Dermatol. 2016 Aug;28(4):444-50.

10. The effectiveness of finasteride and dutasteride used for 3 years in women with androgenetic alopecia. Boersma IH, Oranje AP, Grimalt R, Iorizzo M, Piraccini BM, Verdonschot EH. Indian J Dermatol Venereol Leprol. 2014 Nov-Dec;80(6):521-5.

11. Mesotherapy using dutasteride-containing preparation in treatment of female pattern hair loss: photographic, morphometric and ultrustructural evaluation. Moftah N, Moftah N, Abd-Elaziz G, Ahmed N, Hamed Y, Ghannam B, Ibrahim M. J Eur Acad Dermatol Venereol. 2013 Jun;27(6):686-93.

12. Oral bicalutamide for female pattern hair loss: A pilot study. Fernandez-Nieto D, Saceda-Corralo D, Rodrigues-Barata R, Hermosa-Gelbard A, Moreno-Arrones O, Jimenez-Cauhe J, Ortega-Quijano D, Vano-Galvan S. Dermatol Ther. 2019 Nov;32(6):e13096.

13. Safety of oral bicalutamide in female pattern hair loss: a retrospective review of 316 patients. Ferial Ismail F, Meah N, de Carvalho LT, Bhoyrul B, Wall D, Sinclair R. J Am Acad Dermatol. 2020 Mar 22:S0190-9622(20)30452-7.8.

14. Sinclair, Rodney D. “Female pattern hair loss: a pilot study investigating combination therapy with low-dose oral minoxidil and spironolactone.” International journal of dermatology 57.1 (2018): 104-109.

15. Low-Dose Oral Minoxidil for Female Pattern Hair Loss: A Unicenter Descriptive Study of 148 Women. Rodrigues-Barata R, Moreno-Arrones OM, Saceda-Corralo D, Jiménez-Cauhé J, Ortega- Quijano D, Fernández-Nieto D, Jaén-Olasolo P, Vaño-Galvan S. Skin Appendage Disord. 2020 Jun;6(3):175-176

Where we see patients?

Clinics in Madrid

Grupo Pedro Jaén is a medical group with more than thirty years of experience, specialising in medical, surgical and aesthetic solutions related to skin health and care. Under the leadership of Dr Pedro Jaén, the group has a multidisciplinary team of highly qualified specialists, ensuring expert care across all areas of treatment. In addition, Grupo Pedro Jaén is recognised for its strong commitment to medical education, its leadership in clinical research and its network of clinics in Madrid, from which it provides healthcare of the highest quality and excellence to its patients.

Grupo Pedro Jaén - Cinca 30

Calle Cinca 30

Located in the El Viso district, this centre houses the consultations of the Hair Disorders and Hair Transplant Unit of Grupo Pedro Jaén in central Madrid.

Mon - Fri: 09:00 - 20:30

Calle Cinca 30, El Viso neighbourhood, Chamartín District, 28002 Madrid

Exterior of the Grupo Pedro Jaén clinic in La Moraleja

La Moraleja

Located in Plaza de La Moraleja, this exclusive centre allows Grupo Pedro Jaén to bring its medical and aesthetic services closer to patients across the entire northern area of Madrid.

Mon - Thu: 09:30 - 20:00 / Fri: 10:00 - 18:00

Calle de la Estafeta 8, ground floor, La Moraleja, 28109 Alcobendas, Madrid, Spain

Related units and pages

Hair Disorders Unit

A specialised medical team and the most effective treatments for all types of hair disorders.

Topical and oral medication

Evidence-based prescription of the most advanced medications for male and female alopecia.

Hair mesotherapy

Microinjection of medications and substances derived from regenerative medicine techniques.

Hair transplant

En varones y mujeres, cuando se ha perdido densidad capilar y se busca recuperarla de forma notoria

Hair loss diagnosis

Diagnosis of alopecia using advanced technology and an expert medical team to determine the most appropriate therapeutic approach.

Female alopecia

Individualised diagnosis and specific treatments for the different types of alopecia in women.

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