Facial wrinkles
At our centres in Madrid: Serrano 143, Serrano 166 and La Moraleja
Specialists in
Treatment of wrinkles and expression lines
Over time, and due to external factors such as sun exposure and hormonal changes, the skin gradually ages. This leads to thinning, and a loss of elasticity and firmness, resulting in the appearance of fine lines and wrinkles, which can vary in type and be caused by different factors. This variety means each type of line and wrinkle will require a different treatment by experienced specialists, such as those at the Grupo Pedro Jaén Facial Aesthetics Unit.
Recognised reference clinics in Spain
Home > Aesthetic Medicine > Facial Aesthetic Medicine > Facial Wrinkles
What sets us apart
Experienced professionals and access to advanced treatments
Advances in technology have transformed facial aesthetics, offering highly effective, minimally invasive solutions to combat wrinkles. The experts of our Facial Aesthetics Unit combine these tools with techniques such as neuromodulators, facial fillers and collagen stimulators for effective results. Surgical treatments are also available when necessary.
Neuromodulators
Advanced laser technology
Radiofrequency microneedling
Thermage radiofrequency
Chemical peels
Biostimulators: natural revitalisation
Injectable resorbable fillers
Plastic surgery for complex cases
Neuromodulators
Neuromodulator injections, commonly known as anti-wrinkle injections, are the most effective treatment for expression lines in the upper third of the face. The procedure uses strategically placed microinjections to relax the muscles responsible for forehead lines, frown lines and crow’s feet, helping to achieve a rejuvenated appearance while preserving natural facial expressions. The treatment is rapid, causes little discomfort and requires no recovery time.
Selective muscle relaxation
Placing the appropriate dose of product precisely on the area responsible for excessive muscle contraction achieves a noticeable reduction in expression lines. The effect begins to be noticeable after 48-72 hours and lasts for a period of four to six months, depending on the individual patient.
Fast and effective results
This is a minimally invasive method, so patients can resume their daily routine immediately. The procedure smooths existing lines and acts as a preventive treatment, slowing down the formation of new wrinkles. Because of their versatility and safety, neuromodulators represent an ideal choice for those seeking facial rejuvenation without resorting to more aggressive solutions.
Advanced laser technology
Laser treatment is one of the most versatile options for addressing aesthetic concerns, offering remarkable results in facial rejuvenation and the correction of skin imperfections. At Grupo Pedro Jaén, we have the largest private laser platform in Europe, allowing us to treat all signs of ageing, including wrinkles and expression lines.
CO2 laser resurfacing
The CO₂ laser is the gold standard among laser resurfacing treatments for skin rejuvenation. It works by removing superficial layers of skin and stimulating collagen production, thus reducing the appearance of wrinkles and pigmentation and improving skin texture. It is ideal for treating photoageing and scars. Results are visible within a few days of application and improve progressively, restoring a firmer, more even and more luminous appearance to the skin. Depending on the treatment intensity, it may involve peeling and a few days of recovery.
Other rejuvenation lasers
In addition to CO₂ and picosecond lasers, other lasers used to treat wrinkles include the Erbium:YAG laser, ideal for fine lines; fractional non-ablative lasers (such as Fraxel®), which require minimal recovery time; the Nd:YAG laser, which improves skin tone and firmness; and intense pulsed light (IPL), effective for reducing pigmentation and redness, and improving skin texture. The specialists at the Facial Aesthetics Unit will make the appropriate treatment choice according to each patient’s needs.
Radiofrequency microneedling
Fractional radiofrequency microneedling combines the mechanical effect of needles with the induction of heat in the deep layers of the skin. This synergy stimulates collagen and elastin production, resulting in a visible improvement in skin tone and firmness. In addition, this technique acts on scars and wrinkles, reducing their appearance without the need for invasive surgery or long recovery periods.
Suitable for specific wrinkles
Its effectiveness is particularly visible in areas such as the nasolabial folds and between the eyebrows, where wrinkles can become pronounced over time. It’s also used to treat sagging in the lower third of the face and to combat loss of definition near the mouth, resulting in smoother, softer skin.
Cumulative results
Although the results are noticeable immediately after the session, they become progressively more evident in the following weeks, when the newly formed collagen finishes structuring the tissue. The number of sessions recommended varies according to the severity of the problem but skin quality improves with each session.
Thermage radiofrequency
This is a non-invasive radiofrequency treatment designed to tighten and firm the skin, improving its texture and contour without the need for surgery. It works by emitting monopolar radiofrequency energy that heats the deep layers of the skin, stimulating collagen production and encouraging skin remodelling. This process helps to reduce sagging and to define the facial contours, as well as smoothing wrinkles and fine lines.
Non-invasive and lasting treatment
The results are progressive, although they begin to be seen from the first few weeks, and can last between 12 and 18 months, depending on each patient. The procedure is safe, rapid and only leaves the face reddened and slightly swollen for a few hours. No recovery time is required, allowing an immediate return to normal activities. It is ideal for visible and natural rejuvenation without surgery and is an excellent option for prevention or maintenance.
Advanced equipment
The Grupo Pedro Jaén Facial Aesthetic Unit has the most advanced version of this radiofrequency equipment, the Thermage FLX. This equipment incorporates an improved cooling system and vibration at the applicator tip for a more comfortable patient experience. It also enables the session to be performed up to 25% faster, as it makes real-time adjustments to the energy parameters according to the skin’s resistance.
Chemical peels
Chemical peels are extremely effective procedures for renewing the skin’s surface and correcting signs of ageing. By applying specific acids, superficial layers are removed, promoting cell regeneration and stimulating collagen production. As a result, imperfections such as fine lines or pigmentation are reduced and the complexion looks more even and luminous.
Blue peel, the gold standard of peels
The blue peel is a medium-deep chemical peel formulated using trichloroacetic acid (TCA) and a distinctive blue dye to guide its application. It improves skin texture, tone and firmness, as well as reducing pigmentation and fine wrinkles. It is ideal for a comprehensive rejuvenation of the face with visible results after the peeling and recovery period.
Combined protocols
The blue peel can be combined with CO2 laser resurfacing for a much more powerful synergistic effect. In such cases, to avoid patient discomfort, the procedure is performed in the operating theatre under anaesthesia and conscious sedation. This non-surgical treatment achieves a spectacular rejuvenating effect that patients say can last 10-15 years.
Biostimulators: natural revitalisation
Biostimulators offer an effective option to improve skin firmness, elasticity and texture from within. When injected at specific points, these compounds stimulate the formation of new collagen, restoring volume and diminishing deep wrinkles without altering the natural expression of the face. The aim is to reinforce the skin structure, progressively achieving a fresher and more youthful appearance.
Suitable for deep wrinkles
Areas such as the marionette lines or nasolabial folds benefit considerably from this treatment, as they often present marked creases that disrupt facial harmony. By gradually filling these areas, biostimulators transform the appearance from within, boosting hydration and tissue density with each application.
Visible long-term improvements
Although the changes may initially be subtle, over the weeks skin will become visibly firmer with fewer imperfections. As collagen synthesis continues after each session, the results are prolonged over time, making sustained rejuvenation possible. In addition, the versatility of this technique enables it to be combined with laser or other procedures to enhance the overall effects.
Injectable resorbable fillers
Empleamos sustancias de relleno reabsorbibles totalmente biocompatibles para reducir la posibilidad de reacciones adversas y evitar el rechazo del material.
Tratamiento para arrugas estáticas
Estas sustancias, también denominadas fillers, ayudan a restaurar volúmenes, de manera que son adecuadas para tratar arrugas estáticas, es decir, aquellas que se mantienen visibles incluso cuando el rostro está en reposo, ya que no están ligadas a la gestualidad. Estas arrugas estáticas suelen aparecer alrededor de la boca (surcos nasogenianos y líneas de marioneta), en las mejillas o bajo los ojos.
Resultados naturales
Gracias a su capacidad de hidratar y retener agua o inducir la producción de colágeno y elastina, estas sustancias de relleno atenúan arrugas profundas y consiguen una superficie cutánea más lisa de manera armónica y natural.
El tratamiento es mínimamente invasivo, no requiere cirugía y se realiza en consulta, sin que sea necesario tiempo de baja o recuperación. Los resultados son visibles de forma inmediata y tienen una duración bastante prolongada, aunque depende del tipo de producto y de la zona tratada. Además de suavizar arrugas, los rellenos dérmicos permiten redefinir contornos, mejorar la calidad de la piel y prevenir el envejecimiento estructural del rostro, siempre que sean aplicados por manos expertas y con criterio médico.
Plastic surgery for complex cases
When non-invasive treatments are unable to provide the desired results, plastic surgery is available as an alternative. Our Plastic Surgery Unit addresses ageing in a holistic manner, using techniques such as facelifts and eyelid surgery (blepharoplasty). These procedures tighten the skin, redefine contours and correct structural defects that can’t be removed by less aggressive methods..
When surgery may be appropriate
Surgical intervention is recommended when there is excess skin or structural damage that limits the effectiveness of other therapies. For example, in accumulations on the neck or very pronounced wrinkles on the face. After a personalised assessment, the most appropriate technique is defined for each patient, ensuring safety and optimum results.
Ideal complement to non-invasive treatments
Rather than replacing other procedures, surgery can be combined with biostimulators, laser therapy or radiofrequency to maximise benefits. This results in lasting improvements and a harmonious appearance. With a holistic approach, the patient experiences a substantial change that enhances both beauty and confidence, achieving a transformation in line with their expectations.
Types, location and treatment options
A guide to understanding facial wrinkles
Facial wrinkles are one of the most visible signs of skin ageing. In addition to chronological ageing, their development is influenced by genetic and hormonal factors, as well as environmental and lifestyle-related factors such as excessive sun exposure, smoking, cosmetic habits and overall lifestyle.
It is also important to distinguish between the different types of wrinkles that appear on the face, particularly dynamic wrinkles (also known as expression lines) and static wrinkles (associated with the progressive loss of skin elasticity that occurs with ageing). The nature and origin of facial wrinkles largely determine the most appropriate treatment approach to reduce their appearance.
Expression lines
Expression lines, or dynamic wrinkles, are directly related to facial movement and muscle activity. They develop when the skin repeatedly folds as a result of contraction of the facial musculature. Although they are exacerbated by the gradual loss of skin elasticity that occurs with age, expression lines are not necessarily age-related.
In fact, some individuals develop expression lines at a young age for a variety of reasons, which may negatively affect facial appearance and give the face a tired, sad or prematurely aged look.
Location and characteristics of expression lines
Expression lines are most commonly found in the following areas:
Forehead
Forehead expression lines typically appear as horizontal lines across the forehead. They are mainly caused by repeated eyebrow elevation and may appear clustered above the eyebrows or extend across the entire forehead. They are more common in highly expressive individuals and tend to become more pronounced over time.
Glabellar area (between the eyebrows)
Glabellar lines form vertically between the eyebrows due to the action of the corrugator muscles. Also known as superciliary muscles, these small muscles are located obliquely in the eyebrow region and are involved in frowning and movement of the upper eyelids. Depending on the strength and symmetry of muscle contraction, glabellar lines may appear as paired lines or be more marked on one side.
As with other expression lines, glabellar wrinkles tend to deepen with age. However, they are also very common in younger individuals who frequently frown, such as people with myopia who squint to see at a distance, patients with photophobia or marked light sensitivity, or individuals with very light-coloured eyes.
Crow’s feet
Periocular wrinkles, commonly known as crow’s feet, often appear relatively early due to two main factors: facial movement and the specific characteristics of the skin around the eyes.
Crow’s feet are linked to the action of the orbicularis oculi muscle, a ring-shaped facial muscle that surrounds the eye and is involved in blinking (specifically eye closure) as well as in what is known as a genuine smile. This muscle is activated during smiling and laughter, while remaining relatively inactive during a social or forced smile. These wrinkles tend to appear earlier and be more pronounced because the skin around the eyes is thinner and contains lower levels of collagen and elastin, making it more vulnerable to dehydration and loss of firmness.
Nasolabial folds
Also known as smile lines, these expression lines extend from the base of the nose towards the corners of the mouth, either obliquely or vertically. They become more noticeable when smiling, which is why they are often visible from an early age without necessarily causing an aesthetic concern.
However, cumulative sun damage and age-related skin laxity contribute to their progressive deepening, which can eventually lead to so-called marionette lines, giving the face a downturned or tired appearance.
Perioral area
Wrinkles in this area, commonly referred to as “barcode lines”, are fine vertical expression lines that appear around the mouth, particularly on the upper lip. They are mainly caused by frequent and forceful pursing of the lips, although they are significantly aggravated by smoking, excessive sun exposure and inadequate hydration of the area.
Other areas
Other facial regions may also develop expression lines, including the sides of the nose, the chin and the vertical bands of the neck. These wrinkles result from exaggerated facial movements during speaking or gesturing. Although they tend to worsen over time, they are not necessarily a direct consequence of normal ageing.
Treatments for expression lines
Injectable treatment
The most effective treatment for expression lines involves the injection of small doses of a medication that relaxes the facial muscles, preventing excessive contraction and the subsequent formation of wrinkles on the skin surface. This medication acts in a highly targeted manner at the injection site and does not affect surrounding tissues.
The goal of this injectable treatment is to prevent wrinkle formation while preserving natural facial expression. Achieving this requires an in-depth understanding of facial anatomy and precise injection techniques tailored to each treatment area.
This is a very safe procedure, performed in the clinic and typically completed in around 20 minutes. As with any injectable treatment, mild discomfort or small pinpoint bleeding at the injection site may occur, although these effects are minimal and do not require specific medical treatment. Patients can resume normal activities immediately. The effects usually begin to appear within 24 to 48 hours, with full results becoming visible approximately two weeks after treatment. In most cases, a follow-up visit is scheduled to assess the outcome and make any necessary adjustments.
The result is a refreshed appearance with relaxed, natural facial expressions that are both subtle and harmonious.
The effects of injectable treatment for expression lines typically last between four and six months, depending on the treated area. Treatment can be repeated once this period has elapsed. Clinical experience has shown that better results are achieved with smaller doses administered more frequently, rather than higher doses spaced further apart.
Other treatment options
There are additional options for reducing expression lines that focus on improving skin quality by stimulating collagen and elastin production. These include biostimulation using regenerative medicine techniques, radiofrequency treatments, dermal fillers and collagen stimulators, as well as laser skin rejuvenation. In most cases, these treatment options are combined with injectable muscle-relaxing therapy to achieve a more comprehensive and balanced rejuvenation outcome.
In most cases, these treatment options are combined with injectable muscle-relaxing therapy to achieve a more comprehensive and balanced rejuvenation outcome.
The specialists of the Grupo Pedro Jaén Facial Aesthetics Unit are pioneers in the treatment of expression lines and have extensive experience in the application of all available therapeutic options.
“In most cases, the best results are achieved by combining different therapeutic options and acting at an early stage.”
Static wrinkles
Static facial wrinkles are associated with a deterioration in skin quality and the natural loss of skin volume, commonly referred to as skin laxity. Skin laxity is characterised by reduced firmness and sagging of the tissues due to the progressive decline in collagen and elastin that occurs naturally over time. This process usually begins around the age of 35 and becomes more pronounced from approximately 40 years of age onwards.
However, the normal ageing and laxity process may be significantly exacerbated by external factors such as cumulative sun damage, skin dehydration, smoking, lack of sleep, and certain skin conditions, including psoriasis or atopic dermatitis. All of these factors can negatively affect overall skin health and contribute to the development of wrinkles.
Static wrinkles tend to appear in areas where facial movement and expression have led to deep crease formation over time, such as the forehead or nasolabial folds. They may also affect the neck, the lower third of the face and the perioral region.
Treatments for static wrinkles
Treatment of static wrinkles is based on filling deep lines and folds, as well as stimulating collagen and elastin production through different therapeutic approaches. The aim is to restore volume, improve skin support and reduce wrinkles associated with skin laxity.
Collagen is a structural protein that plays a key role in the integrity and strength of supporting tissues and is therefore essential for skin density and firmness. Elastin, on the other hand, is responsible for skin elasticity and flexibility, allowing the skin to recover its shape despite the repeated movements, gestures and mechanical stress it is exposed to on a daily basis.
The injection of resorbable dermal fillers involves administering small amounts of a biocompatible material widely used in various medical fields due to its ability to retain water. Depending on its formulation and density, this substance can be used to improve skin hydration, fill deep lines and wrinkles, or restore volume in selected areas.
Collagen stimulators, in turn, are resorbable substances injected into targeted areas to stimulate the production of collagen and elastin, helping to reduce skin laxity and thinning, which are responsible for static wrinkles.
hese treatments are performed in the consultation setting and are administered using needles or cannulas of different calibres. Their effects last for a variable period ranging from six months to two years, depending on the substance and its formulation. Once this period has elapsed and the material has been fully reabsorbed by the body, the procedure can be safely repeated.
As with expression lines, static wrinkles can be treated using different therapeutic combinations to achieve optimal results. Accordingly, the Facial Aesthetics Unit at Grupo Pedro Jaén may combine these procedures with regenerative techniques, radiofrequency systems, ultrasound, rejuvenation laser treatments or microneedling radiofrequency, depending on each patient’s needs.
More information
Below you will find the authorship and references for the information provided on this page:
Authorship and references
The content of this page has been prepared by the Communication Department and the Medical Team of Grupo Pedro Jaén, in line with our editorial commitment to ensuring the accuracy and up-to-date nature of the information provided.
References on facial wrinkles:
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Where we see patients?
Clinics in Madrid
Grupo Pedro Jaén is a medical group founded more than three decades ago with the aim of providing medical, surgical and aesthetic solutions related to skin health and appearance. Led by Dr Pedro Jaén, the group has a highly specialised medical team that covers every area of care with top-level specialists, carries out extensive training activities, is a leader in medical research, and operates several clinics in Madrid, from which it offers the highest standards of care and clinical excellence to all patients.
Calle Serrano 143
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Located in Plaza de La Moraleja, this exclusive centre allows Grupo Pedro Jaén to bring its medical and aesthetic services closer to patients across the entire northern area of Madrid.
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Calle de la Estafeta 8, ground floor, La Moraleja, 28109 Alcobendas, Madrid, Spain
Calle Serrano 166
This centre currently offers services in body aesthetic medicine, endocrinology, nutrition, complementary aesthetic medicine and post-surgical aesthetic treatments.
Mon - Fri: 09:00 - 21:00 / Sat: 09:00 - 14:00
Calle Serrano 166, El Viso neighbourhood, Chamartín district, 28002 Madrid
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