Preventive facial rejuvenation
At our centres in Madrid: Serrano 143, Serrano 166 and La Moraleja
Recognised reference clinics in Spain
Home > Aesthetic Medicine > Facial Aesthetic Medicine > Preventive facial rejuvenation
What sets us apart
Holistic approach to slow the signs of ageing
Prevention is the best tool to fight the signs of ageing before they appear. At Grupo Pedro Jaén, we’ve developed a unique approach based on the concept of prejuvenation: caring for and treating the skin from an early stage to maintain skin health and a youthful appearance. We combine advanced technologies with personalised treatments, achieving natural results that respect each patient’s individual characteristics.
Personalised diagnosis
Chemical peels
Preventive laser
Facial mesotherapy
Neuromodulators
Radiofrequency
What it is, when to start and treatment options
A guide to understanding preventive facial rejuvenation
In modern societies, expectations go far beyond meeting basic healthcare needs. When this principle is applied to health, it becomes clear that as science and medicine have successfully addressed the most serious and life-threatening conditions, attention has increasingly shifted towards therapies and strategies that allow people to enjoy a better quality of life and to age in a healthy and active way.
As a result, the concept of health has evolved to include wellbeing. At Grupo Pedro Jaén, while our primary objective is to help patients maintain healthy skin, we also place great importance on ensuring that they feel comfortable and confident with their appearance.
Achieving this goal requires introducing the concept of prevention. This involves adopting healthy lifestyle habits early on, but also implementing timely medical interventions aimed at preventing or minimising the impact of age-related skin changes.
The concept of prejuvenation
Given that the passage of time is inevitable, it might be assumed that there is little that can be done in a dermatology consultation to prevent the signs of ageing. However, this is far from the case. For several years now, Grupo Pedro Jaén has been working within the framework of what is known as prejuvenation — a term used to describe the approach of caring for the skin and applying selected medical aesthetic treatments at an early stage in order to delay visible signs of ageing.
From a dermatological perspective, it is essential to start from the premise that healthy skin is the foundation. Any preventive treatment or cosmetic strategy must therefore be preceded by the diagnosis and management of underlying skin conditions such as acne, rosacea or sensitive skin.
Once skin health has been stabilised, personalised treatments and skincare can be introduced to protect the skin and provide active ingredients that not only hydrate and support the skin barrier, but also include sun protection to reduce ultraviolet radiation damage — the main cause of photoageing — antioxidants to counteract free radicals, exfoliating acids to promote skin renewal, and biological or laser-based therapies to stimulate the body’s natural regenerative mechanisms. All interventions are selected according to each patient’s individual needs.
Ultimately, the aim is not to alter facial appearance or expression, but to combine medical procedures in a way that achieves harmonious, natural and balanced results through gentle, carefully designed protocols that deliver meaningful benefits.
“In most cases, the best results are achieved by combining different therapeutic options and acting at an early stage.”
When to start preventive facial rejuvenation and main approaches
Preventive facial rejuvenation should begin in childhood and continue throughout adolescence, adulthood and later life. Initiating early, well-planned anti-ageing care from the age of 25–30, using moderate, minimally invasive treatments tailored to specific areas after careful assessment, allows for particularly effective long-term results.
During childhood
Skin care should begin in childhood with sun protection. This is a fundamental measure to prevent sunburn, which is associated with an increased risk of skin cancer later in life. It is well established that the skin has a form of “memory” and that cumulative ultraviolet damage and sunburns experienced before the age of eighteen are directly related to the development of skin cancer in adulthood. In addition, sun exposure is a primary cause of photoageing — a combination of wrinkles, pigmentation and loss of luminosity that leads to premature skin ageing.
During adolescence
At this stage of life, it is essential to establish proper cleansing and hydration routines in order to maintain healthy skin, which is the basis of an attractive appearance. Cleansing is a fundamental step in any facial care routine at any age, while hydration helps preserve the integrity of the skin barrier. The skin barrier, or hydrolipidic mantle, prevents transepidermal water loss and protects the body from the penetration of potentially harmful external agents.
Around the age of 25–30
Basic preventive anti-ageing strategies should be introduced around the age of 25–30. Although this may initially seem early, it is in fact the optimal moment to act, as natural skin regeneration mechanisms begin to slow down at this stage. Supporting these processes helps maintain higher skin quality, slows deterioration and preserves a fresh, youthful appearance for longer.
When we refer to intervention in the late twenties or early thirties, we are not suggesting invasive procedures or high product volumes. Rather, the focus is on addressing early signs that may indicate future concerns, such as expression lines, acne marks, scars or early skin laxity, as well as correcting non-age-related features that can be safely and effectively treated in a facial aesthetics consultation, such as nasal irregularities, lip asymmetries or a gummy smile.
Preventive rejuvenation treatments
Within preventive facial rejuvenation, particular importance is given to treatments aimed at renewing the skin surface and to regenerative procedures designed to stimulate improvement from within.
Gentle chemical peels
By applying masks formulated with chemical exfoliating agents, it is possible to gently exfoliate the superficial layers of the skin, promoting renewal and achieving a clean, fresh and luminous appearance in just a few minutes. These treatments also help soften fine lines that precede deeper wrinkles, deeply cleanse the pores—making them less visible—and reduce early pigmentation changes that may appear at a young age.
Depending on the condition and needs of the skin, these peels can be complemented with superficial mesotherapy. This combination enhances skin quality not only through the microneedling effect itself, which activates the skin’s natural repair mechanisms, but also by delivering active ingredients directly to nourish the skin, increase density and improve tone.
Microneedling
Microneedling involves passing a device equipped with fine needles over the face to create microchannels in the dermis, triggering the skin’s repair mechanisms and increasing collagen and elastin production through controlled micro-injury. The procedure is completed by applying vitamin C or hyaluronic acid through gentle massage, facilitating deeper penetration of these active ingredients. This treatment is used to enhance skin luminosity and smoothness, reduce acne scars and marks, and achieve a more even skin tone.
Low-intensity laser
Low-intensity laser treatments are indicated for acne, including its inflammatory stages, as well as for the marks left by comedones. Early intervention is essential to minimise and soften scars before they become established. Laser therapy also improves the appearance of thickened skin, enlarged pores and prominent facial telangiectasias, contributing to a more uniform and refined complexion.
Radiofrequency and ultrasound
These treatments are particularly suitable for addressing skin laxity from its earliest stages. When applied regularly as part of maintenance sessions within our Beauty and Wellness Unit, they help keep the epidermis clean and hydrated, promote firmer and more resilient skin, and slow down the ageing process. In addition, these technologies have variants specifically designed to treat both facial and body skin laxity.
Treatment of expression lines
The infiltration of small doses of a neuromodulating medication that relaxes the muscles of the upper third of the face (forehead, glabellar area and crow’s feet) helps to retrain facial expressions at an early stage and prevents the formation of expression lines that may give the face a tired, sad or angry appearance. This approach is also particularly useful for preventing wrinkles associated with hyperkinetic facial gestures—where muscles contract excessively—or hypertonic expressions, in which muscles fail to fully relax.
Body treatments
Both our Body Aesthetics Unit and our Beauty and Wellness Unit offer treatments to address body contour concerns at any age. Technologies such as radiofrequency, ultrasound and lymphatic drainage therapies help improve oxygenation, enhance circulation, promote tissue drainage and prevent fluid retention—factors that contribute to a more sculpted and even silhouette.
The aim of preventive rejuvenation treatments is to intervene early in the factors that contribute to skin ageing, slowing down this process and delaying the appearance of visible signs as much as possible. This is always based on the understanding that prejuvenation treatments do not replace essential skincare measures such as sun protection, cleansing and hydration, nor should they be used as a substitute for healthy lifestyle habits.
More information
Below you will find the authorship and references for the information provided on this page:
Authorship and references
The content of this page has been prepared by the Communication Department and the Medical Team of Grupo Pedro Jaén, in line with our editorial commitment to ensuring the accuracy and up-to-date nature of the information provided.
References on preventive facial rejuvenation:
1. Sieber DA, Kenkel JM. Noninvasive Methods for Lower Facial Rejuvenation. Clin Plast Surg. 2018 Oct;45(4):571-584. doi: 10.1016/j.cps.2018.06.003. Epub 2018 Jul 31. PMID: 30268243.
2. Robinson DM, Aasi SZ. Cosmetic concerns and management strategies to combat aging. Maturitas. 2011 Nov;70(3):256-60. doi: 10.1016/j.maturitas.2011.07.020. Epub 2011 Aug 27. PMID: 21873005.
3. Bass LS. Injectable Filler Techniques for Facial Rejuvenation, Volumization, and Augmentation. Facial Plast Surg Clin North Am. 2015 Nov;23(4):479-88. doi: 10.1016/j.fsc.2015.07.004. PMID: 26505544.
4. Thomas JR. Update on Facial Skin Rejuvenation Technology. Facial Plast Surg Clin North Am. 2020 Feb;28(1):xi. doi: 10.1016/j.fsc.2019.10.001. PMID: 31779947.
5. Alster TS, Lupton JR. Nonablative cutaneous remodeling using radiofrequency devices. Clin Dermatol. 2007 Sep-Oct;25(5):487-91. doi: 10.1016/j.clindermatol.2007.05.005. PMID: 17870527.
6. Heitmiller K, Ring C, Saedi N, Biesman B. Nonsurgical Light and Energy-Based Devices: Utility in Eyelid and Periorbital Surgery. Facial Plast Surg Clin North Am. 2021 May;29(2):323-334. doi: 10.1016/j.fsc.2021.01.007. Epub 2021 Apr 24. PMID: 33906764.
7. Sundaram H, Kiripolsky M. Nonsurgical rejuvenation of the upper eyelid and brow. Clin Plast Surg. 2013 Jan;40(1):55-76. doi: 10.1016/j.cps.2012.08.009. PMID: 23186756.
8. Khan U, Khalid N. A Systematic Review of the Clinical Efficacy of Micro-Focused Ultrasound Treatment for Skin Rejuvenation and Tightening. Cureus. 2021 Dec 4;13(12):e20163. doi: 10.7759/cureus.20163. PMID: 35003992; PMCID: PMC8722640.
9. Fabi SG. Noninvasive skin tightening: focus on new ultrasound techniques. Clin Cosmet Investig Dermatol. 2015 Feb 5;8:47-52. doi: 10.2147/CCID.S69118. PMID: 25709486; PMCID: PMC4327394.
10. Mansouri Y, Goldenberg G. Update on hyaluronic acid fillers for facial rejuvenation. Cutis. 2015 Aug;96(2):85-8. PMID: 26367746.
11. Zouboulis CC, Ganceviciene R, Liakou AI, Theodoridis A, Elewa R, Makrantonaki E. Aesthetic aspects of skin aging, prevention, and local treatment. Clin Dermatol. 2019 Jul-Aug;37(4):365-372. doi: 10.1016/j.clindermatol.2019.04.002. Epub 2019 Apr 26. PMID: 31345325.
12. Beer KR. Combined treatment for skin rejuvenation and soft-tissue augmentation of the aging face. J Drugs Dermatol. 2011 Feb;10(2):125-32. PMID: 21283916.
13. Sarić D. Cosmetic applications of botulinum toxin in oculofacial region. Acta Clin Croat. 2010 Dec;49(4):525-8. PMID: 21830467.
14. Lee JC, Daniels MA, Roth MZ. Mesotherapy, Microneedling, and Chemical Peels. Clin Plast Surg. 2016 Jul;43(3):583-95. doi: 10.1016/j.cps.2016.03.004. Epub 2016 May 11. PMID: 27363773.
15. Pathak A, Mohan R, Rohrich RJ. Chemical Peels: Role of Chemical Peels in Facial Rejuvenation Today. Plast Reconstr Surg. 2020 Jan;145(1):58e-66e. doi: 10.1097/PRS.0000000000006346. PMID: 31881607.
16. Samargandy S, Raggio BS. Skin Resurfacing Chemical Peels. 2022 May 1. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan–. PMID: 31613532.
17. Spataro EA, Dierks K, Carniol PJ. Microneedling-Associated Procedures to Enhance Facial Rejuvenation. Facial Plast Surg Clin North Am. 2022 Aug;30(3):389-397. doi: 10.1016/j.fsc.2022.03.012. PMID: 35934440.
18. El-Domyati M, Barakat M, Awad S, Medhat W, El-Fakahany H, Farag H. Multiple microneedling sessions for minimally invasive facial rejuvenation: an objective assessment. Int J Dermatol. 2015 Dec;54(12):1361-9. doi: 10.1111/ijd.12761. Epub 2015 Jun 20. PMID: 26096653.
19. El-Domyati M, El-Ammawi TS, Medhat W, Moawad O, Mahoney MG, Uitto J. Multiple minimally invasive Erbium: Yttrium Aluminum Garnet laser mini-peels for skin rejuvenation: an objective assessment. J Cosmet Dermatol. 2012 Jun;11(2):122-30. doi: 10.1111/j.1473-2165.2012.00606.x. PMID: 22672276; PMCID: PMC3376014.
20. Spataro EA, Dierks K, Carniol PJ. Microneedling-Associated Procedures to Enhance Facial Rejuvenation. Facial Plast Surg Clin North Am. 2022 Aug;30(3):389-397. doi: 10.1016/j.fsc.2022.03.012. PMID: 35934440.
21. Badran KW, Nabili V. Lasers, Microneedling, and Platelet-Rich Plasma for Skin Rejuvenation and Repair. Facial Plast Surg Clin North Am. 2018 Nov;26(4):455-468. doi: 10.1016/j.fsc.2018.06.007. Epub 2018 Aug 16. PMID: 30213427.
22. Beasley KL, Weiss RA. Radiofrequency in cosmetic dermatology. Dermatol Clin. 2014 Jan;32(1):79-90. doi: 10.1016/j.det.2013.09.010. PMID: 24267424.
23. Alexiades M. Microneedle Radiofrequency. Facial Plast Surg Clin North Am. 2020 Feb;28(1):9-15. doi: 10.1016/j.fsc.2019.09.013. PMID: 31779946.
24. Kleidona IA, Karypidis D, Lowe N, Myers S, Ghanem A. Fractional radiofrequency in the treatment of skin aging: an evidence-based treatment protocol. J Cosmet Laser Ther. 2020;22(1):9-25. doi: 10.1080/14764172.2019.1674448. Epub 2019 Dec 11. PMID: 31825296.
Where we see patients?
Clinics in Madrid
Grupo Pedro Jaén is a medical group founded more than three decades ago with the aim of providing medical, surgical and aesthetic solutions related to skin health and appearance. Led by Dr Pedro Jaén, the group has a highly specialised medical team that covers every area of care with top-level specialists, carries out extensive training activities, is a leader in medical research, and operates several clinics in Madrid, from which it offers the highest standards of care and clinical excellence to all patients.
Calle Serrano 143
This centre is the main headquarters of Grupo Pedro Jaén. It provides diagnostic and treatment services in skin cancer, clinical and aesthetic dermatology, laser treatments and other related specialties.
Mon - Fri: 09:00 - 21:00 / Sat: 09:00 - 14:00
Calle Serrano 143, El Viso neighbourhood, Chamartín district, 28006 Madrid, Spain
La Moraleja
Located in Plaza de La Moraleja, this exclusive centre allows Grupo Pedro Jaén to bring its medical and aesthetic services closer to patients across the entire northern area of Madrid.
Mon - Thu: 09:30 - 20:00 / Fri: 09:30 - 18:00
Calle de la Estafeta 8, ground floor, La Moraleja, 28109 Alcobendas, Madrid, Spain
Calle Serrano 166
This centre currently offers services in body aesthetic medicine, endocrinology, nutrition, complementary aesthetic medicine and post-surgical aesthetic treatments.
Mon - Fri: 09:00 - 21:00 / Sat: 09:00 - 14:00
Calle Serrano 166, El Viso neighbourhood, Chamartín district, 28002 Madrid
Related units and pages
Facial aesthetics
Minimally invasive treatments to improve facial appearance with harmonious and natural-looking results.
Body aesthetics
A personalised approach combining different treatment strategies to address the main body-related concerns.
Male aesthetics
Surgical and aesthetic treatments fully adapted to male facial and body anatomy.
Scars
Fully personalised treatments tailored to the type and specific characteristics of each scar.
Plastic surgery
Treatment of facial and body aesthetic and functional concerns that require a surgical solution.
Complementary aesthetics
Cosmetic and aesthetic treatments that address beauty from a clinical perspective to achieve optimal results.
Information and news
Press room
In the Grupo Pedro Jaén Press Room you can find information, advice and news related to dermatology, aesthetic medicine, trichology and general health. The group’s journals are also shared through an online platform, along with updates on the activity and media appearances of our clinics and healthcare professionals.
How Prostate Conditions Can Affect Male Sexual Health
Learn how prostate conditions affect male sexual health and which treatments are most effective while minimising potential long-term effects.
Will Retinol Be Banned in the European Union?
Some patients ask whether retinol will be banned in the EU. In this article, we explain the restrictions that have actually been established.
Blog
News about Grupo Pedro Jaén. Information and advice on dermatology, aesthetic medicine, trichology, and general health
Media
Information about media appearances by our clinics and medical specialists.
Journal
Archive of all Grupo Pedro Jaén journals, available through an external online platform.













